This operation requires IIS integrated pipeline mode in global.asax

This operation requires IIS integrated pipeline mode in global.asax

I have added below code in my application to remove headers to leak
information
protected void Application_PreSendRequestHeaders(object sender, EventArgs e)
{
Response.Headers.Remove("X-Powered-By");
Response.Headers.Remove("X-AspNet-Version");
Response.Headers.Remove("X-AspNetMvc-Version");
Response.Headers.Remove("Server");
}
But when i run my site i am getting error of 'This operation requires IIS
integrated pipeline mode'